Perimenopause is the transition before menopause marked by fluctuating estrogen, changing cycles, and symptoms like sleep disruption, mood changes, hot flashes, and cognitive concerns.

Primary ovarian insufficiency (POI) and surgical menopause cause early estrogen loss, affecting bone, cardiovascular, and brain health, including in women undergoing preventive ovary removal.

This article reviews evidence on common menopause supplements, offering clear guidance on effectiveness, safety, and whether they’re worth trying.